@neWorld® is an award winning educational and social support intervention that uses the Internet as a community-building tool for hospitals and schools. It provides educational continuity for children and adolescents undergoing treatment for cancer and is designed to operate on a small, lightweight laptop featuring a built-in Webcam to facilitate use for both inpatients and outpatients, although it is accessible from any computer. Animated interactive Agents provide online help to the patient, and a proprietary Web-based "mood engine" tailors the look and feel of the site design based on the patient’s health status and mood. Teacher and healthcare provider interfaces enable interaction with the patient and make it possible to download curricula and class content. Usability testing was completed at the Communications Technology Branch of the National Cancer Institute and the Website has won the World Wide Web Health Award. Efficacy testing in a clinical trial with 38 pediatric cancer patients was completed in 2004 and demonstrated that @neWorld has a positive effect on school achievement and self esteem, and reduces behavioral problems. Hospitals participating in the study include Ronald McDonald Children’s Hospital, Children’s Memorial Hospital, Hope Children’s Hospital, and the University of Wisconsin-Madison Children’s Hospital. Ongoing support of this project is provided by the Leap of Faith Foundation.